Aminomethyl Resin

AM resin possesses the following characteristics and applications:

Flexible acylation modification: It allows for rapid acylation with carboxylic acid-containing linkers through standard amide bond formation methods (such as DIC/HOBt or EDC/HCl coupling reagents), providing a highly functionalizable support for solid-phase organic synthesis (SPOS).

Biphasic application compatibility: Solid-phase synthesis: As a universal carrier, it is suitable for constructing molecular libraries containing amide bonds. Liquid-phase synthesis scavenger: By selectively capturing excess electrophilic reagents (such as acid chlorides, activated esters), it purifies the reaction system without interfering with non-electrophilic reagents (such as amines, alcohols), significantly simplifying the post-processing procedure